Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL265238

CCc1ccc(O)cc1.N

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
HSD17B10 Q99714 3/20 0.61
MEN1 O00255 2/20 0.61
MAPT P10636 2/20 0.61
HPGD P15428 2/20 0.61
ALOX15 P16050 2/20 0.61
BLM P54132 2/20 0.61
KMT2A Q03164 2/20 0.61
APAF1 O14727 1/20 0.61
USP2 O75604 1/20 0.61
POLB P06746 1/20 0.61
GAA P10253 1/20 0.61
ALOX12 P18054 1/20 0.61
MAPK1 P28482 1/20 0.61
CASP1 P29466 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
ESR1 P03372 7/20 0.55
ESR2 Q92731 3/20 0.55
ADRA2A P08913 2/20 0.50
ADORA3 P0DMS8 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28148524 0.97 ALDH1A1 (0.64) ALDH1A1HSD17B10MEN1MAPTHPGD
SCHEMBL28713 0.97
Ethane SCHEMBL16114596 0.94 ALDH1A1 (0.61) ALDH1A1HSD17B10MEN1MAPTHPGD
SCHEMBL27808383 0.94 ALDH1A1 (0.61) ALDH1A1HSD17B10MEN1MAPTHPGD
Water SCHEMBL28098300 0.94 ALDH1A1 (0.61) ALDH1A1HSD17B10MEN1MAPTHPGD
SCHEMBL27587206 0.94 ALDH1A1 (0.61) ALDH1A1HSD17B10MEN1MAPTHPGD
SCHEMBL27712317 0.94 ALDH1A1 (0.61) ALDH1A1HSD17B10MEN1MAPTHPGD
SCHEMBL27541364 0.94 ALDH1A1 (0.61) ALDH1A1HSD17B10MEN1MAPTHPGD
Hydrochloric Acid SCHEMBL7071404 0.94 ALDH1A1 (0.61) ALDH1A1HSD17B10MEN1MAPTHPGD
Ammonia Solution, Strong SCHEMBL324960 0.92 ALDH1A1 (0.55) ALDH1A1HSD17B10MEN1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160053040-A1 REINFORCING AGENT FOR POLYCARBONATE RESIN, POLYCARBONATE RESIN COMPOSITION, AND MOLDED ARTICLE MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-25 US disclosed
US-8431378-B2 Aminotransferase, gene encoding the same, and methods of using them KANEKA CORPORATION (JP) 2013-04-30 US disclosed
US-20120164724-A1 NOVEL AMINOTRANSFERASE, GENE ENCODING THE SAME, AND METHODS OF USING THEM KANEKA CORPORATION (JP) 2012-06-28 US disclosed
US-8133705-B2 Aminotransferase, gene encoding the same, and method of using them KANEKA CORPORATION (JP) 2012-03-13 US disclosed
US-20100285544-A1 Novel aminotransferase, gene encoding the same, and method of using them KANEKA CORPORATION (JP) 2010-11-11 US disclosed
EP-1889907-B1 NOVEL AMINO GROUP TRANSFERASE, GENE ENCODING THE SAME AND METHOD OF USING THE SAME KANEKA CORP (JP) 2009-09-02 EP disclosed
EP-1045025-B1 (S)-alpha-PHENETHYLAMINE : PYRUVATE TRANSAMINASE KANEKA CORP (JP) 2008-10-22 EP disclosed
EP-1889907-A1 NOVEL AMINO GROUP TRANSFERASE, GENE ENCODING THE SAME AND METHOD OF USING THE SAME Kaneka Corporation (JP) 2008-02-20 EP disclosed
US-6346402-B1 ACTS ON OPTICALLY ACTIVE (S)-ALPHA-PHENETHYLAMINE AND PYRUVIC ACID TO FORM ACETOPHENONE AND ALANINE; FOR PRODUCING CHEMICAL INTERMEDIATES OF DRUGS AND AGRICULTURAL CHEMICALS KANEKA CORPORATION (JP) 2002-02-12 US disclosed
EP-1045025-A1 (S)-alpha-PHENETHYLAMINE : PYRUVATE TRANSAMINASE KANEKA CORPORATION (JP) 2000-10-18 EP disclosed
EP-0563132-A1 TETRAPEPTIDE DERIVATIVES AND ANALOGUES. BLACK JAMES FOUNDATION (GB) 1993-10-06 EP disclosed
EP-0077202-B1 PROCESS FOR HYDROXYLATING OLEFINS USING OSMIUM-HALOGEN COMPOUND CATALYSTS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-04-09 EP disclosed
EP-0077201-B1 HYDROXYLATION OF OLEFINS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-01-15 EP disclosed
US-4486613-A CATALYTIC OXIDATION EXXON RESEARCH & ENGINEERING CO. (US) 1984-12-04 US disclosed
EP-0104873-A2 A process for hydroxylating olefins using an osmium carbonyl catalyst EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-04-04 EP disclosed
EP-0102154-A1 Process for hydroxylating olefins using a supported osmium catalyst EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-03-07 EP disclosed
US-4413151-A WITH WATER AND OXIDIZER EXXON RESEARCH & ENGINEERING CO. (US) 1983-11-01 US disclosed
US-4390739-A Hydroxylation of olefins EXXON RESEARCH & ENGINEERING CO. (US) 1983-06-28 US disclosed
EP-0077202-A2 Process for hydroxylating olefins using osmium-halogen compound catalysts EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-04-20 EP disclosed
EP-0077201-A2 Hydroxylation of olefins EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-04-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100285544-A1 Novel aminotransferase, gene encoding the same, and method of using them BCAT1, AGXT, ALDH7A1 ALDH1A1 144/4885HSD17B10 118/4885MEN1 4076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.