Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | GCK | P35557 | 3/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652305 | 0.76 | SLC6A3 (0.54) | SLC6A3LMNASLC6A2SLC6A4 | |
| SCHEMBL2652710 | 0.75 | LMNA (0.44) | SLC6A3LMNASLC6A2SLC6A4 | |
| SCHEMBL2653272 | 0.74 | LMNA (0.43) | SLC6A3LMNASLC6A2SLC6A4 | |
| SCHEMBL2652972 | 0.73 | SLC6A3 (0.53) | SLC6A3LMNASLC6A2SLC6A4GCK | |
| SCHEMBL2651736 | 0.73 | LMNA (0.42) | SLC6A3LMNASLC6A2SLC6A4 | |
| SCHEMBL2653094 | 0.73 | LMNA (0.43) | SLC6A3LMNASLC6A2SLC6A4GCK | |
| SCHEMBL2668851 | 0.73 | LMNA (0.46) | SLC6A3LMNASLC6A2SLC6A4GCK | |
| SCHEMBL2652093 | 0.72 | SLC6A3 (0.42) | SLC6A3LMNASLC6A2SLC6A4GCK | |
| SCHEMBL1107290 | 0.71 | SLC6A3 (0.42) | SLC6A3LMNASLC6A2SLC6A4GCK | |
| SCHEMBL2652777 | 0.71 | SLC6A3 (0.41) | SLC6A3LMNASLC6A2SLC6A4GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305301-A1 | ALPHA-ACYL AND ALPHA-HETEROATOM-SUBSTITUTED BENZENE ACETAMIDE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002008209-A1 | ALPHA-ACYL AND ALPHA-HETEROATOM-SUBSTITUTED BENZENE ACETAMIDE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-31 | — | — | WO | disclosed |