⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13684196 | 0.74 | MEN1 (0.32) | — | |
| SCHEMBL16920699 | 0.72 | MEN1 (0.35) | — | |
| SCHEMBL13075463 | 0.68 | THRB (0.35) | — | |
| SCHEMBL24286488 | 0.68 | PDE5A (0.35) | — | |
| SCHEMBL19053840 | 0.67 | PDE10A (0.31) | — | |
| SCHEMBL22275427 | 0.67 | PRMT1 (0.36) | — | |
| SCHEMBL26525941 | 0.66 | POLB (0.38) | — | |
| SCHEMBL26526252 | 0.66 | PDE10A (0.36) | — | |
| SCHEMBL15912316 | 0.65 | KDM5B (0.34) | — | |
| SCHEMBL19099311 | 0.62 | THRB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089170-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023073090-A1 | IMIDAZOPYRIDINE AMIDES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | Janssen Sciences Ireland Unlimited Company (IE) | 2023-05-04 | — | — | WO | disclosed |