Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23890951 | 0.78 | POLB (0.43) | POLBATMSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL10239531 | 0.71 | POLB (0.43) | POLBATMSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL13360488 | 0.70 | POLB (0.48) | POLBATMSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL10239182 | 0.69 | POLB (0.52) | POLBATMSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL19006734 | 0.69 | POLB (0.52) | POLBATMSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL19055354 | 0.67 | KDM4E (0.43) | POLBATMSMN1; SMN2 | |
| SCHEMBL22166766 | 0.67 | POLB (0.39) | POLBSMN1; SMN2ALDH1A1TP53HPGD | |
| SCHEMBL26525826 | 0.66 | — | — | |
| SCHEMBL13328166 | 0.65 | TP53 (0.39) | POLBATMSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL14278538 | 0.64 | ATM (0.46) | POLBATMSMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089170-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023073090-A1 | IMIDAZOPYRIDINE AMIDES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | Janssen Sciences Ireland Unlimited Company (IE) | 2023-05-04 | — | — | WO | disclosed |