Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 5/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581838 | 0.83 | MAP1LC3B (0.47) | NPC1RAB9AMAOAMAOBKMT2A | |
| SCHEMBL21821844 | 0.83 | MAP1LC3B (0.47) | NPC1RAB9AMAOAMAOBKMT2A | |
| SCHEMBL20808435 | 0.68 | ALDH1A1 (0.40) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL21792641 | 0.67 | MAP1LC3B (0.40) | RAB9AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL29692810 | 0.63 | ALDH1A1 (0.60) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL2206344 | 0.63 | ALDH1A1 (0.60) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL196260 | 0.63 | KMT2A (0.51) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL24379788 | 0.62 | SLC18A3 (0.45) | KMT2AMEN1ALDH1A1KDM1AHTT | |
| SCHEMBL1726142 | 0.62 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL1726140 | 0.62 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632903-B1 | COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF | WIGEN BIOMEDICINE TECH SHANGHAI CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |