Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.61 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2653637 | 0.91 | CYP4A11 (0.67) | CYP4A11CYP4F2LOXL2CA1CA2 | |
| SCHEMBL19002551 | 0.85 | CYP4A11 (0.62) | CYP4A11CYP4F2LOXL2CA1CA2 | |
| SCHEMBL19922221 | 0.83 | CYP4A11 (0.60) | CYP4A11CYP4F2LOXL2CA1CA2 | |
| SCHEMBL10965456 | 0.82 | LOXL2 (0.59) | CYP4A11CYP4F2LOXL2CA1CA2 | |
| Ethylene Glycol SCHEMBL27327703 | 0.81 | CYP4A11 (0.56) | CYP4A11CYP4F2LOXL2CA1CA2 | |
| Hydrochloric Acid SCHEMBL6364657 | 0.81 | LOXL2 (0.57) | CYP4A11CYP4F2LOXL2CA1CA2 | |
| SCHEMBL70185 | 0.80 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2CA1CA2 | |
| SCHEMBL8337316 | 0.80 | CYP4A11 (0.60) | CYP4A11CYP4F2LOXL2CA1CA2 | |
| SCHEMBL2655571 | 0.79 | CYP4A11 (0.79) | CYP4A11CYP4F2LOXL2CA1CA2 | |
| SCHEMBL11476011 | 0.79 | CYP4A11 (0.59) | CYP4A11CYP4F2LOXL2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957068-A2 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | Eli Lilly & Company (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007120270-A2 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |
| EP-1758853-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123668-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-29 | — | — | WO | disclosed |