SCHEMBL70185

SCHEMBL70185

COC(=O)c1ccc(CCc2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4A11 Q02928 2/20 0.75
CYP4F2 P78329 1/20 0.72
LOXL2 Q9Y4K0 1/20 0.70
ALDH1A1 P00352 3/20 0.65
HPGD P15428 2/20 0.65
HSD17B10 Q99714 2/20 0.65
TP53 P04637 1/20 0.65
CYP1A2 P05177 1/20 0.65
CYP3A4 P08684 1/20 0.65
CYP2C9 P11712 1/20 0.65
ALOX15 P16050 1/20 0.65
ALOX12 P18054 1/20 0.65
CYP2C19 P33261 1/20 0.65
CKS1B P61024 1/20 0.65
SKP2 Q13309 1/20 0.65
HIF1A Q16665 1/20 0.65
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
TDP1 Q9NUW8 1/20 0.61
CA12 O43570 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8662716 0.92 CA1 (0.77) CYP4A11CYP4F2LOXL2ALDH1A1HPGD
SCHEMBL12294528 0.92 TDP1 (0.77) CYP4A11CYP4F2LOXL2ALDH1A1HPGD
SCHEMBL1928912 0.92 TSHR (0.67) CYP4A11CYP4F2LOXL2ALDH1A1HPGD
SCHEMBL12294447 0.90 CA1 (0.78) CYP4A11CYP4F2LOXL2ALDH1A1HPGD
SCHEMBL28266082 0.90 CA1 (0.78) CYP4A11CYP4F2LOXL2ALDH1A1HPGD
SCHEMBL12294453 0.90 MEN1 (0.65) CYP4A11CYP4F2LOXL2ALDH1A1HPGD
SCHEMBL16687961 0.90 ALDH1A1 (0.69) CYP4A11CYP4F2LOXL2ALDH1A1HPGD
SCHEMBL12176925 0.90 LOXL2 (0.65) CYP4A11CYP4F2LOXL2ALDH1A1HPGD
SCHEMBL15437144 0.90 MEN1 (0.65) CYP4A11CYP4F2LOXL2ALDH1A1HPGD
SCHEMBL1426157 0.90 CYP4A11 (0.68) CYP4A11CYP4F2LOXL2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115772058-B Reduction method of aromatic internal olefins 南通大学 2024-08-16 CN disclosed
US-20230120881-A1 BINUCLEAR GOLD(I) COMPOUNDS FOR PHOTOCATALYSIS APPLICATIONS University of Hong Kong Versitech Limited (CN) 2023-04-20 US disclosed
CN-115772058-A Reduction method of aromatic internal olefin 南通大学 2023-03-10 CN disclosed
EP-4122940-A1 BINUCLEAR GOLD(I) COMPOUNDS FOR PHOTOCATALYSIS APPLICATIONS Versitech Limited (CN) 2023-01-25 EP disclosed
EP-4122940-A1 BINUCLEAR GOLD(I) COMPOUNDS FOR PHOTOCATALYSIS APPLICATIONS Versitech Limited (CN) 2023-01-25 EP disclosed
EP-2414350-B1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2014-11-12 EP disclosed
US-8802813-B2 Polymer comprising cyclohexylene groups and its use in films with negative optical dispersion MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2014-08-12 US disclosed
US-8802813-B2 Polymer comprising cyclohexylene groups and its use in films with negative optical dispersion MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2014-08-12 US disclosed
US-8796466-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2014-08-05 US disclosed
EP-2451893-B1 POLYMER COMPRISING CYCLOHEXYLENE GROUPS AND ITS USE IN FILMS WITH NEGATIVE OPTICAL DISPERSION MERCK PATENT GMBH (DE) 2013-05-29 EP disclosed
US-20110237636-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-09-29 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-20110077280-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-03-31 US disclosed
WO-2011003505-A1 POLYMER COMPRISING CYCLOHEXYLENE GROUPS AND ITS USE IN FILMS WITH NEGATIVE OPTICAL DISPERSION MERCK PATENT GMBH (DE) 2011-01-13 WO disclosed
US-7304103-B2 One step; high functionality; maintains critical properties; polymer composite materials, molecular electronics, sensor devices WILLIAM MARSH RICE UNIVERSITY (US) 2007-12-04 US disclosed
EP-0396564-A1 PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE DERIVATIVES EASTMAN KODAK COMPANY (US) 1990-11-14 EP disclosed
US-4847407-A INTERMEDIATES FOR POLYESTERS EASTMAN KODAK COMPANY (US) 1989-07-11 US disclosed
WO-1989003380-A1 PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE DERIVATIVES EASTMAN KODAK COMPANY (US) 1989-04-20 WO disclosed
US-4789755-A DEHYDRODIMERIZATION OF METHYL OR PHENYL TOLUATES EASTMAN KODAK COMPANY (US) 1988-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237636-A1 Hepatitis C Virus Inhibitors HAVCR2, EIF2AK2, MAVS CYP4A11 1910/4885CYP4F2 1565/4885LOXL2 3184/4885
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CYP4A11 1392/4885CYP4F2 2876/4885LOXL2 3723/4885
US-20110077280-A1 Hepatitis C Virus Inhibitors HAVCR2, EIF2AK2, MAVS CYP4A11 1910/4885CYP4F2 1565/4885LOXL2 3184/4885
US-20230120881-A1 BINUCLEAR GOLD(I) COMPOUNDS FOR PHOTOCATALYSIS APPLICATIONS PPOX, AP3M1, AP2M1 CYP4A11 690/4885CYP4F2 24/4885LOXL2 2961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.