Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | GCGR | P47871 | 10/20 | 0.43 |
| ▸ | GIPR | P48546 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | GCG | P01275 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107340 | 0.92 | GCGR (0.45) | S1PR3GCGRGIPREPHX2S1PR1 | |
| SCHEMBL2652842 | 0.89 | GCGR (0.42) | S1PR3GCGRGIPREPHX2S1PR1 | |
| SCHEMBL6754090 | 0.89 | EPHX2 (0.45) | GCGRGIPREPHX2GCGCYP2D6 | |
| SCHEMBL2651279 | 0.85 | GCGR (0.48) | GCGRGIPREPHX2CYP2D6 | |
| SCHEMBL4096042 | 0.85 | GCGR (0.49) | GCGRGIPREPHX2CYP2D6SERPINE1 | |
| SCHEMBL2650399 | 0.84 | GCGR (0.50) | GCGRGIPREPHX2CYP2D6SERPINE1 | |
| SCHEMBL6752438 | 0.83 | GCGR (0.50) | S1PR3GCGRGIPR | |
| SCHEMBL4081612 | 0.82 | EPHX1 (0.47) | GCGREPHX2S1PR1CYP2D6HDAC3 | |
| SCHEMBL4081733 | 0.81 | EPHX2 (0.45) | GCGRGIPREPHX2GCGCYP2D6 | |
| SCHEMBL2653167 | 0.81 | GCGR (0.46) | GCGRGIPREPHX2GCGCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127560-A1 | Glucagon antagonists/inverse agonists | MADSEN PETER (DK) | 2004-07-01 | — | — | US | claimed |
| US-6706744-B2 | HYPOGLYCEMIC AGENTS; ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2004-03-16 | — | — | US | claimed |
| WO-2002040444-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127560-A1 | Glucagon antagonists/inverse agonists | GLP1R, GPR119, GCGR | S1PR3 1097/4885GCGR 3/4885GIPR 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.