SCHEMBL26528786

SCHEMBL26528786

Fc1cc(F)cc(-c2ccc3c(c2)c2cc(-c4cc(F)cc(F)c4)ccc2n3-c2ccccc2-c2cccc3ccccc23)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
CA12 O43570 4/20 0.34
CA1 P00915 4/20 0.34
CA2 P00918 4/20 0.34
CA9 Q16790 4/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
MAPK13 O15264 1/20 0.32
GCGR P47871 1/20 0.32
MAPK12 P53778 1/20 0.32
MAPK11 Q15759 1/20 0.32
MAPK14 Q16539 1/20 0.32
MCL1 Q07820 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
PIM1 P11309 2/20 0.32
TDO2 P48775 1/20 0.32
IDO2 Q6ZQW0 1/20 0.32
PGR P06401 1/20 0.31
MAP4K4 O95819 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26528776 0.99 POLB (0.36) POLBCA12CA1CA2CA9
SCHEMBL26528787 0.94 TDP1 (0.39) POLBCA12CA1CA2CA9
SCHEMBL26529010 0.86 MAP4K4 (0.35) TDO2IDO2PGRMAP4K4
SCHEMBL26528785 0.85 NT5E (0.35) POLBCA12CA1CA2CA9
SCHEMBL26374401 0.85 POLB (0.43) POLBCA12CA1CA2CA9
SCHEMBL26529607 0.85 MAP4K4 (0.34) TDO2IDO2PGRMAP4K4
SCHEMBL26528781 0.85 AKT1 (0.36) POLBAKR1C3AKR1C2TDO2IDO2
SCHEMBL26528650 0.84 CA12 (0.39) POLBCA12CA1CA2CA9
SCHEMBL26528762 0.84 SSTR2 (0.34) TDO2IDO2PGRMAP4K4
SCHEMBL26528758 0.83 HTR7 (0.36) TDO2IDO2PGRMAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 POLB 3426/4885CA12 3555/4885CA1 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.