SCHEMBL26529607

SCHEMBL26529607

Fc1cc(F)cc(-c2cc(-c3cc(F)cc(F)c3)cc(-c3ccc4c(c3)c3cc(-c5cc(-c6cc(F)cc(F)c6)cc(-c6cc(F)cc(F)c6)c5)ccc3n4-c3ccccc3-c3cc(F)cc(F)c3)c2)c1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.34
HTR7 P34969 1/20 0.34
SSTR2 P30874 4/20 0.34
NTRK1 P04629 1/20 0.32
NTRK3 Q16288 1/20 0.32
NTRK2 Q16620 1/20 0.32
TDO2 P48775 1/20 0.32
IDO2 Q6ZQW0 1/20 0.32
PGR P06401 2/20 0.32
BRD4 O60885 1/20 0.31
AVPR2 P30518 1/20 0.30
AVPR1A P37288 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529010 0.98 MAP4K4 (0.35) MAP4K4HTR7SSTR2NTRK1NTRK3
SCHEMBL26529605 0.94 MAP4K4 (0.35) MAP4K4HTR7SSTR2PGR
SCHEMBL26528758 0.93 HTR7 (0.36) MAP4K4HTR7SSTR2NTRK1NTRK3
SCHEMBL26529628 0.92 BRD9 (0.33) MAP4K4HTR7SSTR2TDO2IDO2
SCHEMBL26529599 0.92 GRM5 (0.34) MAP4K4HTR7SSTR2TDO2IDO2
SCHEMBL26528772 0.91 HTR7 (0.35) MAP4K4HTR7SSTR2NTRK1NTRK3
SCHEMBL26528767 0.90 NT5E (0.35) MAP4K4HTR7SSTR2TDO2IDO2
SCHEMBL26529581 0.90 MAP4K4 (0.33) MAP4K4HTR7SSTR2NTRK1NTRK3
SCHEMBL26540818 0.90 ICMT (0.37) PGR
SCHEMBL26529626 0.90 ICMT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 MAP4K4 4467/4885HTR7 3455/4885SSTR2 4874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.