Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 4/20 | 0.43 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16602999 | 0.78 | NAALAD2 (0.60) | NQO1MIFTTRFTONAALAD2 | |
| SCHEMBL15744221 | 0.77 | FTO (0.64) | NQO1TTRFTONAALAD2JAK2 | |
| SCHEMBL17956697 | 0.77 | FTO (0.69) | NQO1TTRFTONAALAD2JAK2 | |
| SCHEMBL27254940 | 0.77 | TTR (0.58) | NQO1MIFTTRFTONAALAD2 | |
| SCHEMBL29353892 | 0.77 | FTO (0.63) | NQO1TTRFTONAALAD2JAK2 | |
| SCHEMBL991216 | 0.77 | FTO (0.63) | NQO1TTRFTONAALAD2JAK2 | |
| SCHEMBL20399862 | 0.76 | TTR (0.59) | NQO1MIFTTRFTONAALAD2 | |
| SCHEMBL31435048 | 0.76 | TTR (0.59) | NQO1MIFTTRFTONAALAD2 | |
| SCHEMBL17037385 | 0.75 | FTO (0.66) | NQO1TTRFTONAALAD2JAK2 | |
| SCHEMBL20729847 | 0.75 | FTO (0.66) | NQO1TTRFTONAALAD2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196727-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER AND OTHER PROLIFERATIVE DISEASES | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2023-10-12 | — | — | WO | disclosed |