Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 6/20 | 0.63 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353892 | 1.00 | FTO (0.63) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL15744221 | 0.99 | FTO (0.64) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL17956697 | 0.93 | FTO (0.69) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL29538836 | 0.93 | FTO (0.54) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL16602999 | 0.90 | NAALAD2 (0.60) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL18872864 | 0.90 | FTO (0.65) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL8893358 | 0.89 | NAALAD2 (0.62) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL15045059 | 0.89 | FTO (0.61) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL22863319 | 0.88 | NAALAD2 (0.63) | FTONAALAD2JAK2NQO1NR1H2 | |
| SCHEMBL17037385 | 0.88 | FTO (0.66) | FTONAALAD2JAK2NQO1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773936-A4 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | PENN STATE RES FOUND (US) | 2008-10-08 | — | — | EP | claimed |
| EP-1773936-A2 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-04-18 | — | — | EP | claimed |
| US-20050281884-A1 | Unagglomerated core/shell nanocomposite particles | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-12-22 | — | — | US | claimed |
| WO-2005118702-A2 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-12-15 | — | — | WO | claimed |
| EP-1773936-B1 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | PENN STATE RES FOUND (US) | 2015-09-02 | — | — | EP | disclosed |
| EP-2448864-A2 | SILICA-BASED PARTICLE COMPOSITION | Nalco Company (US) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011028497-A2 | CALCIUM-BASED CARRIER PARTICLES | NALCO COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011028469-A2 | CALCIUM BASED CARRIER PARTICLES | NALCO COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011028496-A2 | CALCIUM BASED CARRIER PARTICLES | NALCO COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
| US-20110046238-A1 | CALCIUM BASED CARRIER PARTICLES | NANOSPECIALTIES, LLC | 2011-02-24 | — | — | US | disclosed |
| US-20110046239-A1 | CALCIUM BASED CARRIER PARTICLES | NANOSPECIALTIES, LLC | 2011-02-24 | — | — | US | disclosed |
| US-20110046241-A1 | CALCIUM BASED CARRIER PARTICLES | NANOSPECIALTIES, LLC | 2011-02-24 | — | — | US | disclosed |
| WO-2011008492-A2 | SILICA-BASED PARTICLE COMPOSITION | NALCO COMPANY (US) | 2011-01-20 | — | — | WO | disclosed |
| WO-2011008484-A2 | SILICA-BASED PARTICLE COMPOSITION | NALCO COMPANY (US) | 2011-01-20 | — | — | WO | disclosed |
| US-20100330366-A1 | SILICA-BASED PARTICLE COMPOSITION | NANOSPECIALTIES, LLC | 2010-12-30 | — | — | US | disclosed |
| US-20100331431-A1 | SILICA-BASED PARTICLE COMPOSITION | NALCO COMPANY | 2010-12-30 | — | — | US | disclosed |
| EP-1773936-A4 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | PENN STATE RES FOUND (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1773936-A2 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-04-18 | — | — | EP | disclosed |
| US-20050281884-A1 | Unagglomerated core/shell nanocomposite particles | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-12-22 | — | — | US | disclosed |
| WO-2005118702-A2 | UNAGGLOMERATED CORE/SHELL NANOCOMPOSITE PARTICLES | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046241-A1 | CALCIUM BASED CARRIER PARTICLES | ORAI1, CA7, ACP1 | FTO 1394/4885NAALAD2 4008/4885JAK2 2614/4885 |
| US-20110046238-A1 | CALCIUM BASED CARRIER PARTICLES | ORAI1, CA7, ACP1 | FTO 1394/4885NAALAD2 4008/4885JAK2 2614/4885 |
| US-20110046239-A1 | CALCIUM BASED CARRIER PARTICLES | ORAI1, CA7, ACP1 | FTO 1394/4885NAALAD2 4008/4885JAK2 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.