Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5518912 | 0.79 | TSHR (0.30) | TSHR | |
| SCHEMBL5518901 | 0.77 | — | — | |
| SCHEMBL2362852 | 0.76 | — | — | |
| SCHEMBL22345324 | 0.74 | MEN1 (0.30) | NOS1 | |
| SCHEMBL5670696 | 0.72 | HTT (0.30) | — | |
| SCHEMBL23873160 | 0.71 | TSHR (0.32) | TSHRNOS1 | |
| SCHEMBL5671157 | 0.71 | NOS1 (0.33) | NOS1 | |
| SCHEMBL5518908 | 0.71 | — | — | |
| SCHEMBL508211 | 0.70 | — | — | |
| SCHEMBL16295346 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532120-A1 | PHENYLPYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004014865-A1 | PHENYLPYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |