SCHEMBL26529015

SCHEMBL26529015

Cc1cc(-c2ccc3c(c2)c2cc(-c4cc(C)cc(C(F)(F)F)c4)ccc2n3-c2ccccc2-c2ccccc2)cc(C(F)(F)F)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ICMT O60725 5/20 0.36
RXRA P19793 3/20 0.35
RXRB P28702 3/20 0.35
TACR1 P25103 6/20 0.34
METAP2 P50579 1/20 0.34
BACE1 P56817 1/20 0.33
KIF11 P52732 1/20 0.33
RXRG P48443 1/20 0.33
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529003 0.99 ICMT (0.36) ICMTRXRARXRBTACR1METAP2
SCHEMBL26528840 0.95 ICMT (0.35) ICMTRXRARXRBTACR1METAP2
SCHEMBL26528835 0.94 PTPN5 (0.35) ICMTRXRARXRBKIF11PDK2
SCHEMBL26528984 0.94 ICMT (0.37) ICMTRXRARXRBRXRGPDK2
SCHEMBL26529498 0.93 ICMT (0.36) ICMTRXRARXRBTACR1KIF11
SCHEMBL26529483 0.92 ICMT (0.36) ICMTRXRARXRBTACR1METAP2
SCHEMBL26528839 0.92 ICMT (0.34) ICMTRXRARXRBTACR1METAP2
SCHEMBL26529348 0.92 ICMT (0.36) ICMTRXRARXRBRXRGPDK2
SCHEMBL26534175 0.91 ICMT (0.42) ICMTRXRARXRBTACR1METAP2
SCHEMBL26528991 0.91 ICMT (0.38) ICMTRXRARXRBTACR1RXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 ICMT 36/4885RXRA 1633/4885RXRB 2498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.