SCHEMBL26529003

SCHEMBL26529003

Cc1cc(-c2ccc3c(c2)c2cc(-c4cc(C)cc(C(F)(F)F)c4)ccc2n3-c2ccccc2-c2ccc(-c3ccccc3)cc2)cc(C(F)(F)F)c1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ICMT O60725 3/20 0.36
KIF11 P52732 1/20 0.36
RXRA P19793 4/20 0.35
RXRB P28702 4/20 0.35
TACR1 P25103 6/20 0.34
PTPN5 P54829 1/20 0.34
METAP2 P50579 1/20 0.33
DHODH Q02127 1/20 0.33
RXRG P48443 2/20 0.33
BACE1 P56817 1/20 0.33
GLO1 Q04760 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529015 0.99 ICMT (0.36) ICMTKIF11RXRARXRBTACR1
SCHEMBL26528835 0.95 PTPN5 (0.35) ICMTKIF11RXRARXRBPTPN5
SCHEMBL26529498 0.94 ICMT (0.36) ICMTKIF11RXRARXRBTACR1
SCHEMBL26528840 0.94 ICMT (0.35) ICMTKIF11RXRARXRBTACR1
SCHEMBL26528839 0.93 ICMT (0.34) ICMTKIF11RXRARXRBTACR1
SCHEMBL26528984 0.93 ICMT (0.37) ICMTRXRARXRBPTPN5RXRG
SCHEMBL26528970 0.92 RXRA (0.37) ICMTKIF11RXRARXRBTACR1
SCHEMBL26534128 0.92 ICMT (0.41) ICMTKIF11RXRARXRBTACR1
SCHEMBL26529348 0.91 ICMT (0.36) ICMTRXRARXRBRXRG
SCHEMBL26534175 0.90 ICMT (0.42) ICMTKIF11RXRARXRBTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 ICMT 36/4885KIF11 3651/4885RXRA 1633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.