SCHEMBL26529344

SCHEMBL26529344

Fc1ccccc1-c1cc(-c2ccc3c(c2)c2cc(-c4cc(-c5ccccc5F)cc(-c5ccccc5F)c4)ccc2n3-c2ccccc2-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc(-c2ccccc2F)c1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ICMT O60725 8/20 0.37
EPHX2 P34913 1/20 0.35
PDE2A O00408 1/20 0.33
PDE10A Q9Y233 1/20 0.33
GAA P10253 1/20 0.33
ATM Q13315 1/20 0.33
PDK2 Q15119 1/20 0.33
ERBB2 P04626 1/20 0.32
DHODH Q02127 1/20 0.32
GPBAR1 Q8TDU6 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
MAP4K4 O95819 1/20 0.32
PTPRC P08575 1/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26540655 0.94 ICMT (0.38) ICMTEPHX2PDE2APDE10AGPBAR1
SCHEMBL26538526 0.94 ICMT (0.40) ICMT
SCHEMBL26533963 0.92 ICMT (0.41) ICMT
SCHEMBL26529426 0.90 SCD (0.37) ICMTPDK2DHODHAKR1C3AKR1C2
SCHEMBL26540818 0.90 ICMT (0.37) ICMT
SCHEMBL26529328 0.90 ICMT (0.40) ICMTDHODH
SCHEMBL26538507 0.90 KIF11 (0.39) ICMTDHODH
SCHEMBL26539889 0.90 ICMT (0.40) ICMTDHODH
SCHEMBL26540469 0.90 ICMT (0.41) ICMTGAAATM
SCHEMBL26529373 0.89 ICMT (0.40) ICMTDHODHPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 ICMT 36/4885EPHX2 443/4885PDE2A 4081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.