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Sugi Predict / Targets / YTHDF1

YTHDF1

YTH domain-containing family protein 1 · Q9BYJ9 · YTHDF1 on Sugi Atlas →

169 patent compounds predicted against YTHDF1, 59 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL27387656 SCHEMBL27387656 1.00 2/20
SCHEMBL30898232 SCHEMBL30898232 1.00 2/20
SCHEMBL30898260 SCHEMBL30898260 0.78 2/20
SCHEMBL30898225 SCHEMBL30898225 0.73 2/20
SCHEMBL30898254 SCHEMBL30898254 0.72 2/20
SCHEMBL30898241 SCHEMBL30898241 0.62 2/20
SCHEMBL30898280 SCHEMBL30898280 0.56 2/20
SCHEMBL30898226 SCHEMBL30898226 0.53 2/20
SCHEMBL30898248 SCHEMBL30898248 0.51 2/20
SCHEMBL30898272 SCHEMBL30898272 0.50 2/20
SCHEMBL2908586 SCHEMBL2908586 0.47 2/20
SCHEMBL30898181 SCHEMBL30898181 0.47 2/20
SCHEMBL19459471 SCHEMBL19459471 0.46 2/20
SCHEMBL30141144 SCHEMBL30141144 0.46 2/20
SCHEMBL30898239 SCHEMBL30898239 0.46 2/20
SCHEMBL29316587 SCHEMBL29316587 0.46 2/20
SCHEMBL30898259 SCHEMBL30898259 0.44 2/20
SCHEMBL7397450 SCHEMBL7397450 0.44 2/20
SCHEMBL16401423 SCHEMBL16401423 0.44 2/20
SCHEMBL13516703 SCHEMBL13516703 0.42 2/20

Clinical trials — most relevant to YTHDF1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma PHASE2WITHDRAWN
Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment PHASE2COMPLETED
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN) nanUNKNOWN
Prognosis of METTL-14 in Endometrial Carcinoma nanNOT_YET_RECRUITING
Using the Epitranscriptome to Diagnose and Treat Gliomas nanRECRUITING
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study nanNOT_YET_RECRUITING
The Molecular Pathogenesis Study of Cataract nanUNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs nanUNKNOWN
Long Term Prediction of MASH-related HCC Risk by Proteomics nanNOT_YET_RECRUITING
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants nanRECRUITING
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC nanUNKNOWN
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
Target of Suv420h1/2 in Hepatocytes nanRECRUITING
Childhood-Onset Essential Hypertension Natural History Study nanRECRUITING
Exosomal microRNAs as a Biomarker in Panic Disorder and in Response to CBT nanUNKNOWN
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
The Role of FTO Gene Polymorphism and Insulin Preparation in Obesity in Children With Type 1 Diabetes Mellitus nanCOMPLETED
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
The Predictive Value of Guangzhou Panel for Recurrence in Early-stage Colorectal Cancer nanNOT_YET_RECRUITING
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Assessment of microRNAs Role in Familial Mediterranean Fever FMF Pathophysiology nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a YTHDF1 binder may also engage these)

ProteinNameSimilarity
YTHDF3 YTH domain-containing family protein 3 1.000 landscape →
Q8BYK6 — 1.000 Q8BYK6 →
P59326 — 1.000 P59326 →
Q5RFL8 — 1.000 Q5RFL8 →
Q0VCZ3 — 0.996 Q0VCZ3 →
YTHDF2 YTH domain-containing family protein 2 0.993 landscape →
E7F1H9 — 0.992 E7F1H9 →
Q4R5D9 — 0.992 Q4R5D9 →
Q91YT7 — 0.989 Q91YT7 →
Q80TM6 — 0.976 Q80TM6 →
Q9P2N5 — 0.975 Q9P2N5 →
A0JNC2 — 0.974 A0JNC2 →
Q6NZ18 — 0.974 Q6NZ18 →
Q8CGC4 — 0.974 Q8CGC4 →
Q9Y2K5 — 0.973 Q9Y2K5 →
Q6PEH8 — 0.973 Q6PEH8 →
Q2NLB0 — 0.973 Q2NLB0 →
Q9DCB4 — 0.972 Q9DCB4 →
A0A3Q7JC00 — 0.972 A0A3Q7JC00 →
Q9BX40 — 0.972 Q9BX40 →
GATAD2B Transcriptional repressor p66-beta 0.971 landscape →
O09000 — 0.971 O09000 →
Q5SFM8 — 0.971 Q5SFM8 →
Q91VX2 — 0.971 Q91VX2 →
Q921D9 — 0.971 Q921D9 →
UBAP2 Ubiquitin-associated protein 2 0.971 landscape →
Q6PCR6 — 0.970 Q6PCR6 →
A0A9P4XWM4 — 0.970 A0A9P4XWM4 →
A0JM64 — 0.969 A0JM64 →
Q6P6X9 — 0.969 Q6P6X9 →