Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | EGFR | P00533 | 8/20 | 0.55 |
| ▸ | KDR | P35968 | 7/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | PDE5A | O76074 | 1/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PGK1 | P00558 | 2/20 | 0.48 |
| ▸ | KMT5A | Q9NQR1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13975792 | 0.92 | HTT (0.74) | HTTEGFRKDRAPPEHMT2 | |
| SCHEMBL17122655 | 0.89 | HTT (0.70) | HTTEGFRKDRAPPEHMT2 | |
| SCHEMBL20281125 | 0.87 | HTT (0.76) | HTTEGFRKDRAPPPDE5A | |
| SCHEMBL14095331 | 0.85 | HTT (0.72) | HTTEGFRKDRAPPEHMT2 | |
| SCHEMBL14341613 | 0.85 | HTT (0.72) | HTTEGFRKDRAPPEHMT2 | |
| SCHEMBL23260512 | 0.83 | HTT (0.62) | HTTPDE5AEHMT2KMT5A | |
| SCHEMBL20266987 | 0.82 | APP (0.71) | HTTEGFRKDRAPPPDE4A | |
| SCHEMBL17122605 | 0.82 | HTT (0.79) | HTTEGFRKDRAPPEHMT2 | |
| SCHEMBL17122604 | 0.82 | HTT (0.67) | HTTEGFRKDRAPPEHMT2 | |
| SCHEMBL17122658 | 0.81 | HTT (0.66) | HTTEGFRKDRAPPEHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | YTHDF1, YTHDF3, YTHDF2 | HTT 2511/4885EGFR 999/4885KDR 1658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.