SCHEMBL2653377

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12173603	0.84	KIF11 (0.48)	LMNATYRKMT2AKDM4EALDH1A1
	SCHEMBL12525207	0.82	KIF11 (0.53)	KMT2AKDM4EALDH1A1NPC1RAB9A
	SCHEMBL14062459	0.82	KIF11 (0.52)	LMNATYRKMT2AKDM4EALDH1A1
	SCHEMBL12523556	0.82	KIF11 (0.53)	KMT2AKDM4EALDH1A1NPC1RAB9A
	SCHEMBL12524849	0.82	KIF11 (0.53)	KMT2AKDM4EALDH1A1NPC1RAB9A
	SCHEMBL1765328	0.81	KIF11 (0.59)	DEGS1KDM4EALDH1A1NPC1RAB9A
	SCHEMBL24272542	0.79	CCR1 (0.56)	KMT2AKDM4EALDH1A1NPC1RAB9A
	SCHEMBL22059836	0.78	KIF11 (0.42)	KMT2AKDM4EALDH1A1NPC1RAB9A
	SCHEMBL12523552	0.78	NPC1 (0.45)	KMT2AKDM4EALDH1A1NPC1RAB9A
	SCHEMBL12622269	0.78	NPC1 (0.50)	LMNAKMT2AKDM4EALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.