Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 2/20 | 0.40 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | AMD1 | P17707 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17521773 | 0.79 | AHCY (0.44) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20049564 | 0.79 | PDPK1 (0.34) | — | |
| SCHEMBL18571623 | 0.78 | PI4KA (0.62) | NPEPPSPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16424885 | 0.78 | AHCY (0.38) | AHCYNPEPPSADORA2AADORA1P2RX1 | |
| SCHEMBL18512601 | 0.78 | PI4KA (0.54) | NPEPPSPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12280869 | 0.77 | AHCY (0.35) | AHCYNPEPPSPI4KAPI4K2BPI4K2A | |
| SCHEMBL12280360 | 0.77 | PI4KA (0.39) | AHCYNPEPPSPI4KAPI4K2BPI4K2A | |
| SCHEMBL1802098 | 0.77 | RXFP1 (0.37) | AHCYNPEPPSPI4KAPI4K2BPI4K2A | |
| SCHEMBL23776534 | 0.76 | AHCY (0.47) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18512602 | 0.76 | AHCY (0.47) | AHCYPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787833-B2 | Modified cyclic dinucleoside compounds as sting modulators | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787833-B2 | Modified cyclic dinucleoside compounds as sting modulators | STING1, CGAS, IRF3 | AHCY 4633/4885NPEPPS 2068/4885PI4KA 2127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.