Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 5/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30692042 | 1.00 | P4HB (0.47) | P4HBRELAMAPTNPC1RAB9A | |
| SCHEMBL1687353 | 0.86 | RELA (0.58) | RELAMAPTNPC1RAB9APOLB | |
| SCHEMBL1687354 | 0.86 | RELA (0.58) | RELAMAPTNPC1RAB9APOLB | |
| SCHEMBL17978233 | 0.85 | CYP1A1 (0.53) | P4HBRELAMAPTNPC1RAB9A | |
| SCHEMBL19810852 | 0.85 | CYP1A1 (0.53) | P4HBRELAMAPTNPC1RAB9A | |
| SCHEMBL26125660 | 0.81 | TTR (0.56) | NPC1RAB9AMAOBCYP1A2CYP2C9 | |
| SCHEMBL26125665 | 0.81 | TTR (0.56) | NPC1RAB9AMAOBCYP1A2CYP2C9 | |
| SCHEMBL7241285 | 0.77 | PTPN1 (0.50) | MAPTNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7241283 | 0.77 | PTPN1 (0.50) | MAPTNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL1687390 | 0.77 | RELA (0.59) | RELAMAPTPOLBSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186881-A1 | P38 MAP KINASE INHIBITORS FOR USE IN THE TREATMENT OF COLORECTAL CANCER | BADEN-WÜRTTEMBERG STIFTUNG GGMBH (DE) | 2023-10-05 | — | — | WO | disclosed |