SCHEMBL26535638

SCHEMBL26535638

FC(F)(F)c1ccccc1-c1ccccc1-c1cc(-c2ccc3c(c2)c2cc(-c4cc(-c5ccccc5-c5ccccc5C(F)(F)F)cc(-c5ccccc5-c5ccccc5C(F)(F)F)c4)ccc2n3-c2ccccc2C(F)(F)F)cc(-c2ccccc2-c2ccccc2C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.40
KCNN4 O15554 1/20 0.36
NR3C1 P04150 1/20 0.36
PGR P06401 1/20 0.36
AR P10275 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
ALDH1A1 P00352 4/20 0.35
CYP1A2 P05177 4/20 0.35
CYP3A4 P08684 4/20 0.35
TSHR P16473 4/20 0.35
CYP2C19 P33261 4/20 0.35
MAPK1 P28482 3/20 0.35
USP2 O75604 3/20 0.35
CYP2D6 P10635 3/20 0.35
CLK4 Q9HAZ1 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
SCN9A Q15858 3/20 0.34
HIF1A Q16665 2/20 0.34
HSD11B1 P28845 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26534933 0.95 TRPA1 (0.44) TRPA1NR3C1PGRARKDM4E
SCHEMBL26529148 0.93 TRPA1 (0.38) TRPA1KCNN4ARALDH1A1CYP1A2
SCHEMBL26529145 0.93 TRPA1 (0.37) TRPA1KCNN4NR3C1PGRAR
SCHEMBL26529154 0.92 ALDH1A1 (0.37) TRPA1NR3C1PGRARKDM4E
SCHEMBL26537965 0.91 TRPA1 (0.43) TRPA1KCNN4NR3C1PGRAR
SCHEMBL26535874 0.91 TRPA1 (0.43) TRPA1KCNN4NR3C1PGRAR
SCHEMBL26529331 0.90 TRPA1 (0.38) TRPA1KCNN4NR3C1PGRAR
SCHEMBL26539527 0.89 TRPA1 (0.39) TRPA1KCNN4NR3C1PGRAR
SCHEMBL26539879 0.89 TRPA1 (0.40) TRPA1KCNN4NR3C1PGRAR
SCHEMBL26529118 0.88 TRPA1 (0.36) TRPA1KCNN4NR3C1PGRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 TRPA1 42/4885KCNN4 1057/4885NR3C1 3909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.