⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177400 | 0.82 | LMNA (0.34) | — | |
| SCHEMBL5696892 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL19540992 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL6256094 | 0.78 | — | — | |
| SCHEMBL23675571 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL23675573 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL17029138 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL21191043 | 0.78 | — | — | |
| SCHEMBL2123724 | 0.76 | — | — | |
| SCHEMBL7819437 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1759112-A | Benzimidazole derivatives and their use for modulating the GABA- SB A /SB receptor complex | NEUROSEARCH AS (DK) | 2006-04-12 | — | — | CN | disclosed |
| US-20060069135-A1 | Benzimidazole derivatives and their use for modulating the gaba-a receptor complex | NEUROSEARCH A/S (DK) | 2006-03-30 | — | — | US | disclosed |
| EP-1613618-A2 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABA- sb A /sb RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087690-A2 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABA-A RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 2004-10-14 | — | — | WO | disclosed |
| US-6001850-A | HAVING GONADOTROPIN-RELEASING HORMONE ANTAGONISTIC ACTIVITY ARE USEFUL AS PROPHYLACTIC OR THERAPEUTIC AGENTS FOR THE PREVENTION OR TREATMENT OF SEVERAL HORMONE DEPENDENT DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-14 | — | — | US | disclosed |