Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449195 | 0.98 | PCSK9 (0.55) | PCSK9LTA4HMAPK1CYP3A4TSHR | |
| SCHEMBL15351802 | 0.98 | PCSK9 (0.55) | PCSK9LTA4HMAPK1CYP3A4TSHR | |
| SCHEMBL16446602 | 0.98 | PCSK9 (0.55) | PCSK9LTA4HMAPK1CYP3A4TSHR | |
| SCHEMBL1128562 | 0.94 | PCSK9 (0.58) | PCSK9LTA4HMAPK1CYP3A4TSHR | |
| Phosphine SCHEMBL28357175 | 0.93 | PCSK9 (0.56) | PCSK9LTA4HMAPK1CYP3A4TSHR | |
| SCHEMBL1275435 | 0.86 | PCSK9 (0.47) | PCSK9LTA4HMAPK1CYP3A4TSHR | |
| SCHEMBL1491911 | 0.81 | PCSK9 (0.41) | PCSK9LTA4HMAPK1CYP3A4TSHR | |
| SCHEMBL9226569 | 0.81 | PCSK9 (0.47) | PCSK9LTA4HMAPK1CYP3A4TSHR | |
| SCHEMBL1092105 | 0.81 | PCSK9 (0.40) | PCSK9MAPK1CYP3A4TSHRALDH1A1 | |
| SCHEMBL28228486 | 0.80 | CA1 (0.52) | PCSK9LTA4HNR1I2LIPGLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865773-A | Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling | 大连理工大学 | 2024-04-12 | — | — | CN | claimed |
| CN-117417287-A | Carbazole organic compound, and preparation method and application thereof | 天合光能股份有限公司 | 2024-01-19 | — | — | CN | claimed |
| CN-112756012-B | Hydrophilic organic porous polymer supported palladium catalyst, and preparation method and application thereof | 六盘水师范学院 | 2023-03-10 | — | — | CN | claimed |
| CN-110483223-B | Method for preparing diaryl ketone compound by high-efficiency catalysis of palladium pyridine | 陕西师范大学 | 2022-06-07 | — | — | CN | claimed |
| CN-112756012-A | Hydrophilic organic porous polymer supported palladium catalyst and preparation method and application thereof | 六盘水师范学院 | 2021-05-07 | — | — | CN | claimed |
| CN-109053499-B | Diaryl iodonium salt compound and preparation method and application thereof | 上海邦高化学有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-119569754-A | Thiophene pyrrole fused benzothiadiazole dichroic dye and application thereof | 西安工业大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-118388973-A | Benzotriazole dichroic dye and application thereof | 西安近代化学研究所 | 2024-07-26 | — | — | CN | disclosed |
| CN-117865773-A | Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling | 大连理工大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-115368415-B | ClO-/H in detection line granule 2 O 2 Multicolor fluorescent probe of (2), preparation method and application thereof | 徐州医科大学 | 2024-03-12 | — | — | CN | disclosed |
| WO-2024027138-A1 | PREPARATION METHOD FOR 2-PHENYL INDOLE DERIVATIVE AND USE OF SAME | 石河子大学 | 2024-02-08 | — | — | WO | disclosed |
| CN-115181050-B | Preparation method and application of 2-phenylindole derivative | 石河子大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115181050-B | Preparation method and application of 2-phenylindole derivative | 石河子大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-110903317-A | Method for preparing polysubstituted gem-diaryl methyl phosphate compound | 西南大学 | 2020-03-24 | — | — | CN | disclosed |
| CN-108517217-B | Acetylene liquid crystal compound, preparation method thereof, composition containing acetylene liquid crystal compound and high-frequency component containing acetylene liquid crystal medium | 西安近代化学研究所 | 2020-02-14 | — | — | CN | disclosed |
| CN-110760311-A | Lateral methyl poly-biphenyl liquid crystal compound, liquid crystal composition and application thereof | 武汉轻工大学 | 2020-02-07 | — | — | CN | disclosed |
| CN-110746981-A | Liquid crystal composition and application thereof | 武汉轻工大学 | 2020-02-04 | — | — | CN | disclosed |
| CN-108640941-A | Phenyl boron fluorine complex and preparation method and application thereof | 河北科技大学 | 2018-10-12 | — | — | CN | disclosed |
| EP-1856090-A2 | SUBSTITUTED THIOPHENE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006086488-A2 | SUBSTITUTED THIOPHENE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2006-08-17 | — | — | WO | disclosed |