Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28246401 | 0.93 | CA1 (0.55) | CA1CA2ENPP2NR1I2CA12 | |
| SCHEMBL1128562 | 0.85 | PCSK9 (0.58) | ENPP2PCSK9NR1I2CA7CA14 | |
| Phosphine SCHEMBL28357175 | 0.84 | PCSK9 (0.56) | ENPP2PCSK9NR1I2CA7CA14 | |
| SCHEMBL26293815 | 0.83 | CA1 (0.57) | CA1CA2ENPP2NR1I2CA12 | |
| SCHEMBL14983499 | 0.81 | CA1 (0.45) | CA1CA2ENPP2PCSK9NR1I2 | |
| SCHEMBL14997108 | 0.80 | CA1 (0.44) | CA1CA2ENPP2PCSK9NR1I2 | |
| SCHEMBL2653923 | 0.80 | PCSK9 (0.56) | PCSK9NR1I2LTA4HLPLLIPG | |
| SCHEMBL16446602 | 0.79 | PCSK9 (0.55) | PCSK9NR1I2LTA4HNR5A1LPL | |
| SCHEMBL15351802 | 0.79 | PCSK9 (0.55) | PCSK9NR1I2LTA4HNR5A1LPL | |
| SCHEMBL4449195 | 0.79 | PCSK9 (0.55) | PCSK9NR1I2LTA4HNR5A1LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105754588-B | A kind of luminous porous organic polymer material and preparation method of imines connection | 吉林大学 | 2018-07-17 | — | — | CN | disclosed |