Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.74 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 6/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203780 | 0.93 | CYP1A2 (0.76) | CYP1A2SCN5ABRD4METDYRK1A | |
| SCHEMBL20203809 | 0.85 | CYP1A2 (1.00) | CYP1A2SCN5ABRD4DYRK1AMEN1 | |
| SCHEMBL26539288 | 0.85 | CYP1A2 (0.86) | CYP1A2SCN5ABRD4METDYRK1A | |
| SCHEMBL20190585 | 0.81 | CYP1A2 (0.58) | CYP1A2SCN5ABRD4METDYRK1A | |
| SCHEMBL26539322 | 0.80 | CYP1A2 (0.53) | CYP1A2SCN5ADYRK1ACYP3A4FYN | |
| SCHEMBL26539314 | 0.80 | CYP1A2 (0.62) | CYP1A2SCN5AMETDYRK1ACYP3A4 | |
| SCHEMBL20203875 | 0.78 | CYP1A2 (0.58) | CYP1A2SCN5ABRD4METDYRK1A | |
| SCHEMBL26539407 | 0.78 | MET (0.44) | CYP1A2SCN5ABRD4METMEN1 | |
| SCHEMBL937008 | 0.76 | CYP1A2 (0.55) | CYP1A2SCN5ABRD4METMEN1 | |
| SCHEMBL20204036 | 0.75 | CYP1A2 (0.54) | CYP1A2SCN5ADYRK1AFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | CYP1A2 1988/4885SCN5A 8/4885BRD4 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.