Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567572 | 0.80 | PHLPP2 (0.49) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL26560436 | 0.80 | PRSS1 (0.47) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL25686449 | 0.78 | PRSS1 (0.45) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL22423720 | 0.78 | PRSS1 (0.45) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL21896174 | 0.77 | PRSS1 (0.49) | PRSS1TPSAB1PHLPP2TSHRALDH1A1 | |
| SCHEMBL25570107 | 0.76 | PRSS1 (0.43) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL25567568 | 0.76 | PRSS1 (0.43) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL25124090 | 0.75 | TPSAB1 (0.42) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL20630435 | 0.75 | PRSS1 (0.53) | PRSS1TPSAB1HDAC1PHLPP2ALDH1A1 | |
| SCHEMBL21702539 | 0.74 | PRSS1 (0.41) | PRSS1TPSAB1F13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257154-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | Medilink Therapeutics (Suzhou) Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |