Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.40 |
| ▸ | CDK2 | P24941 | 7/20 | 0.40 |
| ▸ | GSK3B | P49841 | 6/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21740947 | 0.82 | LOX (0.49) | LOXLOXL2ACACBFFAR1CCNE1 | |
| SCHEMBL5510542 | 0.82 | LOXL2 (0.59) | LOXLOXL2ACACBFFAR1CCNE1 | |
| SCHEMBL22286716 | 0.82 | LOXL2 (0.59) | LOXLOXL2ACACBFFAR1CCNE1 | |
| SCHEMBL31280150 | 0.82 | LOXL2 (0.59) | LOXLOXL2ACACBFFAR1CCNE1 | |
| SCHEMBL30184846 | 0.81 | LOX (0.57) | LOXLOXL2ACACBFFAR1CCNE1 | |
| SCHEMBL30361238 | 0.81 | LOXL2 (0.62) | LOXLOXL2FFAR1CCNE1CDK2 | |
| SCHEMBL445783 | 0.81 | LOXL2 (0.62) | LOXLOXL2FFAR1CCNE1CDK2 | |
| SCHEMBL2017499 | 0.81 | LOX (0.57) | LOXLOXL2ACACBFFAR1CCNE1 | |
| SCHEMBL26474046 | 0.79 | GABRP (0.41) | FFAR1WNT3AGABRPGABRDGABRA1 | |
| SCHEMBL26544516 | 0.79 | LOX (0.48) | LOXLOXL2ACACBCCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072096-A1 | TETRAHYDROFURAN-CONTAINING POLYCYCLIC DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 优领医药科技(香港)有限公司 | 2023-05-04 | — | — | WO | disclosed |