SCHEMBL26540653

SCHEMBL26540653

Fc1ccccc1-c1ccccc1-n1c2ccc(-c3cc(-c4ccccc4C(F)(F)F)cc(-c4ccccc4C(F)(F)F)c3)cc2c2cc(-c3cc(-c4ccccc4C(F)(F)F)cc(-c4ccccc4C(F)(F)F)c3)ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.40
NR3C1 P04150 1/20 0.39
PGR P06401 1/20 0.39
ALOX5AP P20292 1/20 0.38
FEN1 P39748 1/20 0.38
KCNN4 O15554 1/20 0.37
AR P10275 1/20 0.36
CYP1A2 P05177 5/20 0.36
CYP2C19 P33261 5/20 0.36
CYP3A4 P08684 4/20 0.36
TSHR P16473 4/20 0.36
USP2 O75604 3/20 0.36
CYP2D6 P10635 3/20 0.36
CLK4 Q9HAZ1 3/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPK1 P28482 3/20 0.36
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
SCN9A Q15858 3/20 0.34
HIF1A Q16665 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26540468 0.94 TRPA1 (0.42) TRPA1NR3C1PGRALOX5APFEN1
SCHEMBL26529583 0.93 TRPA1 (0.38) TRPA1NR3C1PGRALOX5APFEN1
SCHEMBL26537965 0.92 TRPA1 (0.43) TRPA1NR3C1PGRALOX5APFEN1
SCHEMBL26529118 0.90 TRPA1 (0.36) TRPA1NR3C1PGRALOX5APFEN1
SCHEMBL26529590 0.89 PTGES2 (0.34) TRPA1
SCHEMBL26529330 0.89 TRPA1 (0.41) TRPA1NR3C1PGRALOX5APFEN1
SCHEMBL26534933 0.89 TRPA1 (0.44) TRPA1NR3C1PGRALOX5APFEN1
SCHEMBL26529579 0.88 MAP4K4 (0.37) TRPA1PGRALOX5APFEN1ALDH1A1
SCHEMBL26540659 0.88 NR3C1 (0.41) TRPA1NR3C1PGRALOX5APFEN1
SCHEMBL26537360 0.88 TRPA1 (0.41) TRPA1NR3C1PGRALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 TRPA1 42/4885NR3C1 3909/4885PGR 3828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.