Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24642496 | 0.84 | FFAR1 (0.45) | ALDH1A1MAPTFFAR1FFAR4MMP2 | |
| SCHEMBL21137867 | 0.81 | CYP1A2 (0.34) | CYP1A2CYP2C9ALDH1A1CYP3A4MAPT | |
| SCHEMBL26603612 | 0.71 | CYP1A2 (0.31) | CYP1A2CYP2C9ALDH1A1CYP3A4MAPT | |
| SCHEMBL22618750 | 0.71 | FAAH (0.36) | CYP1A2CYP2C9ALDH1A1CYP3A4MAPT | |
| SCHEMBL24642858 | 0.70 | FFAR1 (0.36) | CHRNB2CHRNA4FFAR1FFAR4MMP2 | |
| SCHEMBL26493323 | 0.69 | FFAR1 (0.35) | CYP1A2CYP2C19CHRNB2CHRNA4FFAR1 | |
| SCHEMBL26493303 | 0.69 | CYP1A2 (0.35) | CYP1A2CYP2C19CHRNB2CHRNA4FFAR1 | |
| SCHEMBL23193046 | 0.68 | MAPT (0.41) | CYP2C9ALDH1A1CYP3A4MAPTCYP2C19 | |
| SCHEMBL26550832 | 0.68 | FFAR1 (0.34) | CYP1A2CYP2C19CHRNB2CHRNA4FFAR1 | |
| SCHEMBL22561348 | 0.68 | ALDH1A1 (0.32) | CYP1A2CYP2C9ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257154-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | Medilink Therapeutics (Suzhou) Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |