Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | GCGR | P47871 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655395 | 0.90 | GCGR (0.41) | PPARDPPARAPPARGGCGRMRGPRX4 | |
| SCHEMBL2653584 | 0.87 | GCGR (0.56) | PPARDPPARAPPARGGCGR | |
| SCHEMBL2654628 | 0.86 | GCGR (0.43) | PPARDPPARAPPARGGCGR | |
| SCHEMBL2655103 | 0.84 | GCGR (0.47) | PPARDPPARAPPARGGCGR | |
| SCHEMBL2654727 | 0.82 | GCGR (0.55) | PPARDPPARAPPARGGCGR | |
| SCHEMBL2655868 | 0.79 | GCGR (0.46) | PPARDPPARAGCGR | |
| SCHEMBL2655611 | 0.79 | GCGR (0.60) | GCGR | |
| SCHEMBL2655300 | 0.78 | GCGR (0.53) | GCGR | |
| SCHEMBL2654950 | 0.78 | GCGR (0.46) | GCGR | |
| SCHEMBL3040148 | 0.78 | PPARD (0.42) | PPARDSRD5A2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957068-A2 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | Eli Lilly & Company (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007120270-A2 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |