Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26542859 | 1.00 | NPC1 (0.34) | NPC1GAAHDAC1MEN1KMT2A | |
| SCHEMBL26542645 | 0.97 | HDAC1 (0.33) | HDAC1MEN1KMT2APLGPLAU | |
| SCHEMBL26542624 | 0.83 | LNPEP (0.41) | HDAC1MEN1KMT2APLGPLAU | |
| SCHEMBL26544742 | 0.82 | ERAP2 (0.44) | HDAC1MEN1KMT2A | |
| SCHEMBL31311010 | 0.81 | MEN1 (0.39) | NPC1MEN1KMT2ARXFP1POLB | |
| SCHEMBL20764529 | 0.81 | MEN1 (0.38) | MEN1KMT2APLGRXFP1HTT | |
| SCHEMBL20764532 | 0.81 | MEN1 (0.38) | MEN1KMT2APLGRXFP1HTT | |
| SCHEMBL31311139 | 0.79 | F11 (0.36) | MEN1KMT2APOLBMAPT | |
| SCHEMBL17795712 | 0.79 | MAPT (0.45) | NPC1GAAMEN1KMT2AEP300 | |
| SCHEMBL16392510 | 0.79 | MAPT (0.45) | NPC1GAAMEN1KMT2AEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196788-A2 | METAGENOME-GUIDED BIOSYNTHESIS AND COMPOUNDS AND METHODS OF USE THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 2023-10-12 | — | — | WO | disclosed |