Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 14/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956553 | 0.80 | GRM2 (0.45) | GRM2NPC1 | |
| SCHEMBL975383 | 0.78 | GRM2 (0.46) | GRM2NPC1 | |
| SCHEMBL974763 | 0.77 | GRM2 (0.46) | GRM2GPR139NPC1 | |
| SCHEMBL17828279 | 0.75 | GRM2 (0.67) | GRM2NPC1 | |
| SCHEMBL4233106 | 0.75 | GRM2 (0.49) | GRM2NPC1 | |
| SCHEMBL974069 | 0.74 | GRM2 (0.40) | GRM2GPR139NPC1SMN1; SMN2 | |
| SCHEMBL2483181 | 0.74 | GRM2 (0.43) | GRM2GPR139NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29356302 | 0.73 | GRM2 (0.47) | GRM2NPC1 | |
| SCHEMBL19911462 | 0.73 | GRM2 (0.47) | GRM2GPR139NPC1 | |
| SCHEMBL4083654 | 0.73 | GRM2 (0.47) | GRM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11788026-B2 | Hydraulic fluid | AFTON CHEMICAL CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11788026-B2 | Hydraulic fluid | OR10J3, OXSR1, NOX5 | GRM2 835/4885GPR139 809/4885NPC1 1815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.