Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844019 | 0.76 | SMN1; SMN2 (0.49) | LMNAKMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL17844001 | 0.75 | SMN1; SMN2 (0.40) | LMNAKMT2AALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL5729690 | 0.70 | MAPT (0.41) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL10911738 | 0.69 | NLRP3 (0.38) | KMT2AALDH1A1MEN1CYP2C9SMN1; SMN2 | |
| SCHEMBL11215228 | 0.69 | KMT2A (0.40) | LMNAKMT2AALDH1A1MEN1CYP2C9 | |
| SCHEMBL28924301 | 0.69 | ALDH1A1 (0.38) | KMT2AALDH1A1MEN1TSHRPDK1 | |
| SCHEMBL16397799 | 0.69 | S1PR3 (0.41) | KMT2AMEN1PPARGPPARA | |
| SCHEMBL509923 | 0.68 | MEN1 (0.39) | LMNAKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL3201307 | 0.68 | KMT2A (0.36) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6097343 | 0.67 | TSHR (0.44) | LMNAALDH1A1SMN1; SMN2TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807411-A1 | CYANOTHIOPHENES, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-07-18 | — | — | EP | disclosed |
| US-20060094764-A1 | Cyanothiophenes, their preparation and their use in pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-04 | — | — | US | disclosed |
| WO-2006042850-A1 | CYANOTHIOPHENES, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094764-A1 | Cyanothiophenes, their preparation and their use in pharmaceutical compositions | GLRB, GPR6, GRM3 | LMNA 4036/4885KMT2A 4416/4885ALDH1A1 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.