Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 18/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21504007 | 0.90 | ALOX12 (0.79) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL16646138 | 0.90 | ALOX12 (1.00) | ALOX12ALOX15ALDH1A1 | |
| SCHEMBL26547049 | 0.88 | ALOX12 (0.70) | ALOX12ALOX15ALDH1A1 | |
| Vlx-1005 SCHEMBL29598551 | 0.88 | ALOX12 (1.00) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| Vlx-1005 SCHEMBL16646023 | 0.88 | ALOX12 (1.00) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL18356857 | 0.83 | ALOX12 (1.00) | ALOX12ALOX15ALDH1A1 | |
| SCHEMBL16646071 | 0.83 | ALOX12 (0.79) | ALOX12ALOX15ALDH1A1 | |
| SCHEMBL26547018 | 0.78 | ALOX12 (0.78) | ALOX12ALOX15 | |
| SCHEMBL16634463 | 0.77 | ALOX12 (1.00) | ALOX12ALOX15ALDH1A1LMNAGAA | |
| SCHEMBL30891484 | 0.77 | ALOX12 (1.00) | ALOX12ALOX15ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054936-B1 | 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES AS 12-LIPOXYGENASE INHIBITORS | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2023-10-18 | — | — | EP | disclosed |