Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 18/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26546912 | 0.88 | ALOX12 (0.67) | ALOX12MEN1POLBCASP6KMT2A | |
| SCHEMBL16646088 | 0.88 | ALOX12 (1.00) | ALOX12ALOX15 | |
| SCHEMBL26547012 | 0.78 | ALOX12 (0.82) | ALOX12ALOX15 | |
| SCHEMBL27845644 | 0.74 | MEN1 (0.78) | ALOX12MEN1POLBCASP6KMT2A | |
| SCHEMBL21504007 | 0.68 | ALOX12 (0.79) | ALOX12MEN1KMT2AALOX15 | |
| SCHEMBL16646020 | 0.68 | ALOX12 (1.00) | ALOX12KMT2AALOX15 | |
| SCHEMBL16646138 | 0.68 | ALOX12 (1.00) | ALOX12ALOX15 | |
| SCHEMBL16646184 | 0.68 | ALOX12 (1.00) | ALOX12ALOX15 | |
| SCHEMBL27072568 | 0.67 | ALOX12 (0.68) | ALOX12MEN1KMT2AALOX15 | |
| SCHEMBL16646129 | 0.67 | ALOX12 (0.74) | ALOX12MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054936-B1 | 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES AS 12-LIPOXYGENASE INHIBITORS | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2023-10-18 | — | — | EP | disclosed |