Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 5/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.42 |
| ▸ | PDE6D | O43924 | 3/20 | 0.42 |
| ▸ | PDE6A | P16499 | 3/20 | 0.42 |
| ▸ | PDE6G | P18545 | 3/20 | 0.42 |
| ▸ | PDE6B | P35913 | 3/20 | 0.42 |
| ▸ | PDE6C | P51160 | 3/20 | 0.42 |
| ▸ | PDE6H | Q13956 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480887 | 1.00 | PIK3CA (0.45) | PIK3CAPDE2APDE10APDE6DPDE6A | |
| SCHEMBL30480903 | 0.82 | KDM4E (0.34) | PIK3CAPDE2APDE10AALDH1A1POLB | |
| SCHEMBL26547751 | 0.82 | KDM4E (0.34) | PIK3CAPDE2APDE10AALDH1A1POLB | |
| SCHEMBL30480878 | 0.82 | PRKDC (0.44) | PIK3CAMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL26547748 | 0.82 | PRKDC (0.44) | PIK3CAMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL29471279 | 0.78 | BRD4 (0.41) | ALDH1A1POLBBRPF1EHMT2EHMT1 | |
| SCHEMBL26111817 | 0.78 | BRD4 (0.41) | ALDH1A1POLBBRPF1EHMT2EHMT1 | |
| SCHEMBL31496296 | 0.77 | ALDH1A1 (0.42) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL31426266 | 0.76 | TNFRSF1A (0.33) | MEN1ALDH1A1KMT2AP2RY12BRPF1 | |
| SCHEMBL31425838 | 0.76 | ALOX5 (0.37) | MEN1KMT2ABRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322724-A1 | HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2023-10-12 | — | — | US | disclosed |
| US-20230322724-A1 | HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322724-A1 | HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS | EP300, HDAC1, BRD3 | PIK3CA 1790/4885PDE2A 2584/4885PDE10A 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.