SCHEMBL26547769

SCHEMBL26547769

O=Cc1ccc(Oc2ccc(C3(c4ccc(F)cc4)c4ccccc4-c4ccc(Br)cc43)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.37
ALDH1A1 P00352 4/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 3/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
OPRK1 P41145 1/20 0.34
AKR1A1 P14550 1/20 0.34
AKR1B1 P15121 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
DRD1 P21728 2/20 0.32
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD5 P21918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22211055 0.92 ALDH1A1 (0.38) PDK2ALDH1A1KMT2AKDM4ELMNA
SCHEMBL26547815 0.90 PDK2 (0.36) PDK2ALDH1A1KMT2AKDM4ELMNA
SCHEMBL26547829 0.90 PDK2 (0.36) PDK2ALDH1A1KMT2AKDM4ELMNA
SCHEMBL25456242 0.89 PDK2 (0.37) PDK2KMT2AKDM4ELMNASMN1; SMN2
SCHEMBL22197292 0.88 ALDH1A1 (0.40) PDK2ALDH1A1KMT2AKDM4ELMNA
SCHEMBL26547848 0.88 ESR1 (0.39) PDK2KMT2AKDM4ELMNASMN1; SMN2
SCHEMBL21793556 0.86 ADAMTS5 (0.36) PDK2ALDH1A1L3MBTL1KMT2AKDM4E
SCHEMBL21174567 0.84 MEN1 (0.41) PDK2ALDH1A1L3MBTL1KMT2AKDM4E
SCHEMBL30082735 0.84 MEN1 (0.41) PDK2ALDH1A1L3MBTL1KMT2AKDM4E
SCHEMBL26861777 0.82 PDK2 (0.37) PDK2L3MBTL1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219399-A1 COMPOUND, COATING COMPOSITION COMPRISING SAME, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR 주식회사 엘지화학 2023-11-16 WO disclosed
US-20230337530-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor LG CHEM, LTD. (KR) 2023-10-19 US disclosed
US-20230337530-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor LG CHEM, LTD. (KR) 2023-10-19 US disclosed
US-20230329095-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor LG CHEM, LTD. (KR) 2023-10-12 US disclosed
US-20230329095-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor LG CHEM, LTD. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337530-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor NOTUM, OR51E2, ORMDL3 PDK2 3966/4885ALDH1A1 67/4885L3MBTL1 3698/4885
US-20230329095-A1 Novel Compound, Coating Composition Comprising Same, Organic Light-Emitting Device Using Same, and Manufacturing Method Therefor NOTUM, OR51E2, ORMDL3 PDK2 3786/4885ALDH1A1 70/4885L3MBTL1 3870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.