Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.35 |
| ▸ | PRKDC | P78527 | 4/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 3/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.35 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26548078 | 1.00 | PIK3CA (0.35) | PIK3CAPRKDCPIK3C2BPIK3R1PIK3C2A | |
| SCHEMBL26548627 | 0.96 | PIK3CA (0.34) | PIK3CAPRKDCPIK3C2BPIK3R1PIK3C2A | |
| SCHEMBL26548952 | 0.96 | PIK3CA (0.34) | PIK3CAPRKDCPIK3C2BPIK3R1PIK3C2A | |
| SCHEMBL26549125 | 0.90 | GAK (0.37) | PIK3CAPRKDCPIK3C2BPIK3R1PIK3C2A | |
| SCHEMBL26549410 | 0.90 | GAK (0.37) | PIK3CAPRKDCPIK3C2BPIK3R1PIK3C2A | |
| SCHEMBL26564297 | 0.89 | COMT (0.40) | PIK3CAPRKDCPIK3C2BPIK3R1PIK3C2A | |
| SCHEMBL26548272 | 0.89 | PIK3CA (0.34) | PIK3CAPRKDCPIK3C2BPIK3R1PIK3C2A | |
| SCHEMBL26552631 | 0.88 | PIK3CA (0.40) | PIK3CAPRKDCPIK3C2BPIK3R1PIK3C2A | |
| SCHEMBL26548448 | 0.86 | TOP1 (0.40) | PIK3CAPRKDCPIK3C2BPIK3R1PIK3C2A | |
| SCHEMBL26551092 | 0.86 | PIK3CA (0.35) | PIK3CAPRKDCPIK3C2BPIK3R1PIK3C2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230337527-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | LAPTO CO., LTD. (KR) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230337527-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | AOC1, ODC1, PIEZO1 | PIK3CA 4826/4885PRKDC 2422/4885PIK3C2B 4558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.