SCHEMBL26548628

SCHEMBL26548628

FC(F)(F)c1cc(-c2ccc3ccc(-c4ccc(-c5cccc6c5oc5ncccc56)cc4)cc3c2)cc(C(F)(F)F)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 2/20 0.36
PGR P06401 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
KDR P35968 2/20 0.34
EPHX2 P34913 3/20 0.34
MAOB P27338 1/20 0.34
DHODH Q02127 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP1B1 Q16678 1/20 0.33
PIK3C2A O00443 1/20 0.32
PIK3C2B O00750 1/20 0.32
PIK3R1 P27986 1/20 0.32
PIK3CA P42336 1/20 0.32
PRKDC P78527 1/20 0.32
PIK3C3 Q8NEB9 1/20 0.32
RIPK1 Q13546 2/20 0.32
ENPP1 P22413 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548954 1.00 TOP1 (0.36) TOP1PGRSUCNR1KDREPHX2
SCHEMBL26548082 0.97 TOP1 (0.37) TOP1PGRSUCNR1KDREPHX2
SCHEMBL26548457 0.97 TOP1 (0.37) TOP1PGRSUCNR1KDREPHX2
SCHEMBL26548626 0.93 TOP1 (0.43) TOP1PGRSUCNR1EPHX2ENPP1
SCHEMBL26548948 0.93 TOP1 (0.43) TOP1PGRSUCNR1EPHX2ENPP1
SCHEMBL26549412 0.90 TOP1 (0.35) TOP1PGRSUCNR1MAOBTDP1
SCHEMBL26549128 0.90 TOP1 (0.35) TOP1PGRSUCNR1MAOBTDP1
SCHEMBL26548063 0.90 TOP1 (0.43) TOP1PGRSUCNR1EPHX2ENPP1
SCHEMBL26548451 0.90 TOP1 (0.43) TOP1PGRSUCNR1EPHX2ENPP1
SCHEMBL26548796 0.89 MAOB (0.35) TOP1PGRSUCNR1KDRMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 TOP1 1472/4885PGR 4012/4885SUCNR1 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.