SCHEMBL26548856

SCHEMBL26548856

Fc1ccc(-c2ccc3ccc(-c4ccc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)nc4)cc3c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.47
KDM1A O60341 3/20 0.45
NR3C1 P04150 1/20 0.41
PGR P06401 1/20 0.41
GPR55 Q9Y2T6 1/20 0.39
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
PIK3CA P42336 1/20 0.37
NPC1 O15118 2/20 0.36
RXFP1 Q9HBX9 1/20 0.36
PDGFRB P09619 1/20 0.36
PDGFRA P16234 1/20 0.36
TDO2 P48775 3/20 0.36
IDO1 P14902 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548840 0.94 TDP1 (0.44) TDP1KDM1ANR3C1PGRGPR55
SCHEMBL26548858 0.92 KDM1A (0.47) TDP1KDM1ATDO2IDO1TEK
SCHEMBL26548862 0.91 KDM1A (0.49) TDP1KDM1ATDO2IDO1TEK
SCHEMBL26567865 0.91 TDP1 (0.40) TDP1KDM1ANR3C1PGRGPR55
SCHEMBL26548345 0.90 TDP1 (0.45) TDP1KDM1ANR3C1PGRGPR55
SCHEMBL26548833 0.90 KDM1A (0.44) TDP1KDM1ANR3C1PGRPIK3CA
SCHEMBL26548843 0.90 KDM1A (0.44) TDP1KDM1ANR3C1PGRPIK3CA
SCHEMBL26560110 0.90 PDGFRB (0.44) TDP1KDM1ANR3C1PGRGPR55
SCHEMBL26548860 0.86 KDM1A (0.43) TDP1KDM1APGRTDO2IDO1
SCHEMBL26548335 0.86 KDM1A (0.45) TDP1KDM1ANR3C1PGRPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 TDP1 924/4885KDM1A 114/4885NR3C1 2265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.