Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | FPR3 | P25089 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26546972 | 0.85 | RAB9A (0.48) | RAB9ANPC1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL26546979 | 0.84 | RAB9A (0.47) | RAB9ANPC1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL26101907 | 0.84 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2LSSPOLB | |
| SCHEMBL26554844 | 0.83 | SMN1; SMN2 (0.57) | RAB9ANPC1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL26547038 | 0.82 | RAB9A (0.51) | RAB9ANPC1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL26546984 | 0.81 | HTT (0.49) | RAB9ANPC1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL26546975 | 0.81 | HTT (0.49) | RAB9ANPC1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL26097832 | 0.81 | EPHX2 (0.48) | RAB9ANPC1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL23727569 | 0.80 | NAMPT (0.52) | RAB9ANPC1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL26100612 | 0.80 | NAMPT (0.52) | RAB9ANPC1HTTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | NAMPT, MC4R, SIRT1 | RAB9A 807/4885NPC1 463/4885HTT 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.