SCHEMBL26548927

SCHEMBL26548927

FC(F)(F)c1cc(-c2ccc(-c3ccc4ccc(-c5ccc(-c6cccc7cccnc67)cc5)cc4c3)cc2)cc(C(F)(F)F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 3/20 0.46
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GMNN O75496 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MMP2 P08253 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
MMP9 P14780 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
MMP8 P22894 1/20 0.41
CCR1 P32246 1/20 0.41
THPO P40225 1/20 0.41
MTOR P42345 1/20 0.41
HTT P42858 1/20 0.41
MMP13 P45452 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548605 1.00 TOP1 (0.46) TOP1MAPTKDM4EGMNNLMNA
SCHEMBL26548011 0.96 TOP1 (0.47) TOP1MAPTKDM4EGMNNLMNA
SCHEMBL26548421 0.96 TOP1 (0.47) TOP1MAPTKDM4EGMNNLMNA
SCHEMBL26548923 0.92 TOP1 (0.54) TOP1MAPTKDM4EGMNNLMNA
SCHEMBL26548602 0.92 TOP1 (0.54) TOP1MAPTKDM4EGMNNLMNA
SCHEMBL26553308 0.92 TOP1 (0.42) TOP1MAPTKDM4EGMNNLMNA
SCHEMBL26556727 0.92 TOP1 (0.42) TOP1MAPTKDM4EGMNNLMNA
SCHEMBL26566690 0.89 TOP1 (0.40) TOP1MAPTKDM4EGMNNLMNA
SCHEMBL26548008 0.88 TOP1 (0.56) TOP1MAPTKDM4EGMNNLMNA
SCHEMBL26548419 0.88 TOP1 (0.56) TOP1MAPTKDM4EGMNNLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 TOP1 1472/4885MAPT 2621/4885KDM4E 884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.