SCHEMBL26549064

SCHEMBL26549064

Fc1ccc(-c2ccc3cc(-c4ccc(-c5ccncc5)cc4)cnc3c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 9/20 0.62
PDGFRA P16234 9/20 0.62
GAK O14976 1/20 0.60
EGFR P00533 1/20 0.55
MAP4K4 O95819 1/20 0.50
CDK8 P49336 1/20 0.50
CLK2 P49760 1/20 0.50
CDK7 P50613 1/20 0.50
CDK9 P50750 1/20 0.50
CDK5 Q00535 1/20 0.50
ACVR1 Q04771 1/20 0.50
ROCK1 Q13464 1/20 0.50
DYRK1A Q13627 1/20 0.50
LRRK2 Q5S007 1/20 0.50
CLK4 Q9HAZ1 1/20 0.50
DYRK1B Q9Y463 1/20 0.50
ESR2 Q92731 1/20 0.50
MAPK14 Q16539 2/20 0.46
MAPK10 P53779 1/20 0.46
CSF1R P07333 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26549357 1.00 PDGFRB (0.62) PDGFRBPDGFRAGAKEGFRMAP4K4
SCHEMBL26549163 0.92 PDGFRB (0.61) PDGFRBPDGFRAGAKEGFRESR2
SCHEMBL26549437 0.92 PDGFRB (0.61) PDGFRBPDGFRAGAKEGFRESR2
SCHEMBL26549228 0.92 PDGFRB (0.54) PDGFRBPDGFRAGAKEGFRMAP4K4
SCHEMBL26560487 0.85 PDGFRB (0.70) PDGFRBPDGFRAGAKEGFRMAP4K4
SCHEMBL26549438 0.84 PDGFRB (0.51) PDGFRBPDGFRAGAKMAP4K4ESR2
SCHEMBL26560476 0.84 GAK (0.64) PDGFRBPDGFRAGAKEGFRMAP4K4
SCHEMBL26549364 0.84 PDGFRB (0.58) PDGFRBPDGFRAGAKMAP4K4CLK4
SCHEMBL26549330 0.84 PDGFRB (0.54) PDGFRBPDGFRAGAKESR2PIK3CA
SCHEMBL26547982 0.82 MAPK14 (0.53) MAP4K4DYRK1ACLK4MAPK14MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 PDGFRB 4867/4885PDGFRA 4853/4885GAK 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.