SCHEMBL26549183

SCHEMBL26549183

Fc1ccc(-c2ccc3cc(-c4ccc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)cc4)cnc3c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 7/20 0.49
PDGFRA P16234 7/20 0.49
ESR2 Q92731 1/20 0.45
TDP1 Q9NUW8 2/20 0.45
GAK O14976 1/20 0.43
PIK3CA P42336 1/20 0.42
NR3C1 P04150 1/20 0.41
PGR P06401 1/20 0.41
TEK Q02763 2/20 0.41
GPR55 Q9Y2T6 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
GRIN1 Q05586 1/20 0.38
GRIN2B Q13224 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26549442 1.00 PDGFRB (0.49) PDGFRBPDGFRAESR2TDP1GAK
SCHEMBL26550420 1.00 PDGFRB (0.49) PDGFRBPDGFRAESR2TDP1GAK
SCHEMBL26549170 1.00 PDGFRB (0.49) PDGFRBPDGFRAESR2TDP1GAK
SCHEMBL26549172 0.99 PDGFRB (0.48) PDGFRBPDGFRAESR2TDP1GAK
SCHEMBL26558890 0.94 ESR2 (0.50) PDGFRBPDGFRAESR2TDP1GAK
SCHEMBL26549438 0.91 PDGFRB (0.51) PDGFRBPDGFRAESR2GAKPIK3CA
SCHEMBL26550422 0.91 GAK (0.48) PDGFRBPDGFRAESR2TDP1GAK
SCHEMBL26549457 0.91 GAK (0.48) PDGFRBPDGFRAESR2TDP1GAK
SCHEMBL26549177 0.91 GAK (0.48) PDGFRBPDGFRAESR2TDP1GAK
SCHEMBL26549187 0.91 ESR2 (0.46) PDGFRBPDGFRAESR2TDP1GAK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 PDGFRB 4867/4885PDGFRA 4853/4885ESR2 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.