SCHEMBL26549239

SCHEMBL26549239

FC(F)(F)c1cc(-c2ccc3cc(-c4ccc(-c5cnc6ccccc6c5)nc4)cnc3c2)cc(C(F)(F)F)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 2/20 0.45
PIK3CA P42336 2/20 0.45
CYP2A6 P11509 1/20 0.44
BIRC5 O15392 1/20 0.43
PDGFRB P09619 2/20 0.43
PDGFRA P16234 2/20 0.43
MTOR P42345 2/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
PIK3CB P42338 1/20 0.40
PIK3CG P48736 1/20 0.40
MAP4K4 O95819 1/20 0.39
CSNK1G2 P78368 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
MKNK2 Q9HBH9 1/20 0.39
MAP4K5 Q9Y4K4 1/20 0.39
KDM1A O60341 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548215 0.95 PIK3CD (0.44) PIK3CDPIK3CACYP2A6BIRC5PDGFRB
SCHEMBL26548727 0.94 PIK3CD (0.43) PIK3CDPIK3CACYP2A6BIRC5PDGFRB
SCHEMBL26549195 0.93 PIK3CD (0.39) PIK3CDPIK3CACYP2A6BIRC5PDGFRB
SCHEMBL26549235 0.91 PDGFRB (0.50) PIK3CDPIK3CACYP2A6BIRC5PDGFRB
SCHEMBL26549077 0.91 PDGFRB (0.51) PIK3CDPIK3CACYP2A6BIRC5PDGFRB
SCHEMBL26549369 0.91 PDGFRB (0.51) PIK3CDPIK3CACYP2A6BIRC5PDGFRB
SCHEMBL26549319 0.89 IDO1 (0.42) PIK3CDPIK3CAPDGFRBPDGFRAMTOR
SCHEMBL26547997 0.87 PDGFRB (0.53) PIK3CDPIK3CACYP2A6BIRC5PDGFRB
SCHEMBL26548417 0.87 PDGFRB (0.53) PIK3CDPIK3CACYP2A6BIRC5PDGFRB
SCHEMBL26549313 0.86 PDGFRB (0.42) PIK3CAPDGFRBPDGFRAKDM1ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 PIK3CD 4765/4885PIK3CA 4826/4885CYP2A6 2788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.