SCHEMBL26549338

SCHEMBL26549338

FC(F)(F)c1ccc(-c2ccc(-c3ccc4cc(-c5ccc(-c6cccc7ccccc67)cc5)cnc4c3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 1/20 0.43
PDGFRA P16234 1/20 0.43
MTOR P42345 1/20 0.41
CA12 O43570 2/20 0.40
CA9 Q16790 2/20 0.40
BIRC5 O15392 1/20 0.40
SCN5A Q14524 1/20 0.40
SCN9A Q15858 1/20 0.40
CSF1R P07333 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ESR2 Q92731 1/20 0.40
TOP1 P11387 2/20 0.39
PIK3CD O00329 1/20 0.39
PIK3CA P42336 1/20 0.39
HSP90AA1 P07900 1/20 0.39
GAK O14976 1/20 0.39
MAP4K4 O95819 1/20 0.39
ENPP1 P22413 1/20 0.39
TRPV1 Q8NER1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26549048 1.00 PDGFRB (0.43) PDGFRBPDGFRAMTORCA12CA9
SCHEMBL26549341 0.93 MTOR (0.40) PDGFRBPDGFRAMTORCA12CA9
SCHEMBL26549051 0.93 MTOR (0.40) PDGFRBPDGFRAMTORCA12CA9
SCHEMBL26549200 0.91 PDGFRB (0.39) PDGFRBPDGFRAMTORBIRC5CSF1R
SCHEMBL26560306 0.87 BIRC5 (0.49) PDGFRBPDGFRAMTORCA12CA9
SCHEMBL26549336 0.86 PDGFRB (0.46) PDGFRBPDGFRAMTORCA12CA9
SCHEMBL26549043 0.86 PDGFRB (0.46) PDGFRBPDGFRAMTORCA12CA9
SCHEMBL26549331 0.86 PDGFRB (0.50) PDGFRBPDGFRAMTORCA12CA9
SCHEMBL26549366 0.86 PDGFRB (0.58) PDGFRBPDGFRAMTORCA12CA9
SCHEMBL26548383 0.86 CA12 (0.48) CA12CA9SCN5ASCN9ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 PDGFRB 4867/4885PDGFRA 4853/4885MTOR 3806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.