Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GIPR | P48546 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | GCG | P01275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2654973 | 0.94 | ROCK2 (0.38) | GCGRFFAR1FFAR4GIPRPPARD | |
| SCHEMBL2654060 | 0.92 | GCGR (0.40) | GCGRGIPRGCG | |
| SCHEMBL2654589 | 0.84 | GCGR (0.48) | GCGRFFAR1FFAR4GIPRPPARD | |
| SCHEMBL2653538 | 0.83 | GCGR (0.51) | GCGRFFAR1FFAR4GIPRGCG | |
| SCHEMBL2654147 | 0.83 | FFAR1 (0.48) | GCGRFFAR1FFAR4GIPRPPARD | |
| SCHEMBL2667228 | 0.82 | GCGR (0.56) | GCGRGIPRGCG | |
| SCHEMBL1765826 | 0.82 | GCGR (0.56) | GCGRGIPRGCG | |
| SCHEMBL2656415 | 0.82 | GCG (0.41) | GCGRGIPRGCG | |
| SCHEMBL2654507 | 0.82 | GCGR (0.47) | GCGRGIPR | |
| SCHEMBL2654049 | 0.80 | GCGR (0.47) | GCGRGIPRPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758853-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2005123668-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-29 | — | — | WO | claimed |
| EP-1758853-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123668-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-29 | — | — | WO | disclosed |