Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 3/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | MC1R | Q01726 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F12 | P00748 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26550424 | 0.98 | LDHB (0.40) | LDHBNNMTKLKB1KEAP1PLAU | |
| SCHEMBL26549275 | 0.94 | LDHB (0.38) | LDHBNNMTKLKB1KEAP1PLAU | |
| SCHEMBL26548790 | 0.94 | LDHB (0.38) | LDHBNNMTKLKB1KEAP1PLAU | |
| SCHEMBL26549444 | 0.91 | LDHB (0.39) | LDHBNNMTKLKB1KEAP1PLAU | |
| SCHEMBL26548683 | 0.91 | LDHB (0.39) | LDHBNNMTKLKB1KEAP1PLAU | |
| SCHEMBL26549320 | 0.91 | LDHB (0.39) | LDHBNNMTKLKB1KEAP1PLAU | |
| SCHEMBL27005370 | 0.91 | LDHB (0.39) | LDHBNNMTKLKB1KEAP1PLAU | |
| SCHEMBL26549219 | 0.91 | LDHB (0.39) | LDHBNNMTKLKB1KEAP1PLAU | |
| SCHEMBL26549679 | 0.89 | LDHB (0.36) | LDHBNNMTKLKB1KEAP1PLAU | |
| SCHEMBL20442198 | 0.87 | LDHB (0.36) | LDHBNNMTKLKB1KEAP1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306538-A2 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES | Sarepta Therapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| EP-3297649-B1 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES | SAREPTA THERAPEUTICS INC (US) | 2023-10-11 | — | — | EP | disclosed |