Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.35 |
| ▸ | NNMT | P40261 | 2/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | MC1R | Q01726 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22340342 | 0.90 | MC4R (0.35) | LDHBKLKB1NNMTMC4RMC5R | |
| SCHEMBL25589569 | 0.90 | MC4R (0.35) | LDHBKLKB1NNMTMC4RMC5R | |
| SCHEMBL25591860 | 0.88 | MC4R (0.36) | LDHBKLKB1NNMTMC4RMC5R | |
| SCHEMBL26550888 | 0.87 | LDHB (0.39) | LDHBKLKB1NNMTMC4RMC5R | |
| SCHEMBL26548790 | 0.86 | LDHB (0.38) | LDHBKLKB1NNMTMC4RMC5R | |
| SCHEMBL26549275 | 0.86 | LDHB (0.38) | LDHBKLKB1NNMTMC4RMC5R | |
| SCHEMBL26550424 | 0.84 | LDHB (0.40) | LDHBKLKB1NNMTMC4RMC5R | |
| SCHEMBL26549219 | 0.83 | LDHB (0.39) | LDHBKLKB1NNMTMC4RMC5R | |
| SCHEMBL26549320 | 0.83 | LDHB (0.39) | LDHBKLKB1NNMTMC4RMC5R | |
| SCHEMBL26548683 | 0.83 | LDHB (0.39) | LDHBKLKB1NNMTMC4RMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10675356-B2 | Peptide oligonucleotide conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2020-06-09 | — | — | US | disclosed |
| US-20180214567-A1 | Peptide Oligonucleotide Conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180214567-A1 | Peptide Oligonucleotide Conjugates | MYOF, MUSK, MTPN | LDHB 1407/4885KLKB1 813/4885NNMT 3072/4885 |
| US-10675356-B2 | Peptide oligonucleotide conjugates | MYOF, MUSK, MTPN | LDHB 1407/4885KLKB1 813/4885NNMT 3072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.